Fedorov Y. Calcific valvular heart disease: the mechanisms of development, morpho-functional peculiarities of the heart, clinic, diagnosis and approaches to medicamental treatment.

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0504U000314

Applicant for

Specialization

  • 14.01.02 - Внутрішні хвороби

11-05-2004

Specialized Academic Board

Д 20.601.01

Ivano-Frankivsk national medical university

Essay

The object is patients with calcific valvular heart disease(CVHD). Purpose: to determine the spreading, the main risk factors, morphofunctional changes of aortic and mitral valves and myocardium of heart ventriculi, the peculiarities of diagnosis, methods of medicamental therapy of the patients with CVHD. Methods: general clinical, dopplerechocardiograph, immunologic, morphologic. Novelty: spreading of CVHD is determined, risk factors pathomorphogenesis, hemodynamic heart function at early stages of CVHD, peculiarities of differential diagnosis with rheumatism, Lev's disease, estimation of CVHD damage degree and stages, medicamental treatment was applied. Results: there are determined the spreading, risk factors, pathomorphogenesis peculiarities, the changes of diastolicfunction at I-II st. of CVHD,criteria of differential diagnosis, methods of medicamental therapy. It is implemented in health care system in Ukraine; the field is internal diseases

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