Penishkevych Y. The efficiency of differential pathogenically-oriented procedures of treatment in eye trauma clinic

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0505U000071

Thesis Registration Form

0505U000071.pdf

Applicant for

Specialization

  • 14.01.18 - Очні хвороби

17-12-2004

Specialized Academic Board

Д 41.556.01

State Institution "The Filatov Institute of Eye Disease and Tissue Therapy of NAMS of Ukraine"

Essay

Posttraumatic inflammation of an eye. To increase the treatment efficiency of patients with penetrating eye injuries. Methods - biochemical; radioimmunological; ophthalmologic; electrophysiological. Instrumentation: radioimmunological counters, spectrophotometer, US scanner, an electroretinographer, ophthalmoreographer. The role of metabolic, fibrinolysis and a proteolysis changes, eicosanoids status, pro- and antioxidant system snflunce in posttraumatic process is studied. The concept of eicosanoids role in posttraumatic inflammatory process complications development is formulated. The basic directions of complex treatment of patients with penetrating eye injuries are developed: Paracetamolum is more effective than Dexamethazon in wound repair, predicts cornea edema and reduces frequency of descemetitis, prevents synechiae formation, reduces a degree of aqueous humor opacification, a fibrinous exudation and plastic complications, localizes a posttraumatic inflammation, reduces frequency of cases of pupil deformftions and the reaction to light. Obtained results are introduced in clinic and pedagogic process in Bucovinian SMA, Vinnitsa SMU, Dnepropetrovsk SMA, Donetsk SMU, Ivano-Frankivsk SMA, Ternopil SMA, Kharkiv SMU and Kharkiv MAPE. The sphere of use - medicine, ophthalmology.

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