Zavads'kyj O. Influence of temporal bone pneumatisation disorders on the development and course of various forms of middle ear inflammatory diseases

The dissertation is devoted to find a decision in problem of prevention and treatment of middle ear inflammatory diseases. New conception is proposed to describe the mechanism of influence of pneumatisation to development of otitis media purulenta with help of compensatory breathing transformation into anaerobic which depends on cellular system development. Increased amount of big macrofages in middle ear excudate during pneumatisation period provides compensation of immune system malfunction in early age by using fagocytar reaction. It is proved that sclerotic type of mastoid process is not the normal anatomy feature. The cause development of sclerotic and not enough pneumatised process mastoid, their asymmetry is not current inflammatory process but infringed pneumatisation in child age. It is allowed to conclude that secondary inflammatory sclerosis of temporal bone never occurs in case of good pneumatised mastoid. It is shows that malfunction of auditory tube lead to development in sclerotic and poorly pneumatised mastoid. Presence and role of surfactant is revealed in middle ear in chronic otitis purulenta. It's known that development of acute mastoid take place only in significantly pneumatised mastoid process. Complex conservative treatment technique is invented by using oxygen, miramystine and laser radiation which boosts the effective of the treatment, shortens the duration of treatment. Performed work shows that prevention of chronic purulent otitis media is to be started in early age including correct prevention and treatment of acute otitis in that age, allowing mastoid process to be enough pneumatised which will supply the tolerance to inflammatory middle ear disease.