Khukhlina O. "Clinical and pathogenesis features of the current and progression of steatohepatosis and chronic steatohepatitis in patients with insulin resistance syndrome, substantiation of the differentiated treatment"

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0506U000230

Applicant for

Specialization

  • 14.01.02 - Внутрішні хвороби

25-04-2006

Specialized Academic Board

Д 26.613.06

Shupyk National Medical Academy of Postgraduate Education

Essay

The main thesis of dissertation presents the results of a complex study of the clinical, morphological, metabolic, cytokine, hormonal, hemostasis, hemodynamic aspects of different variants of current of nonalcoholic fatty liver disease depending on the degree of insulin resistance. A new conception of pathogenesis of nonalcoholic fatty liver disease, the criteria of diagnostics, programmes of the differentiated therapy were developed. Expediency of using of glutargin, acethylcystein and rosiglitazon in the treatment of nonalcoholic steatohepatosis and chronic steatohepatitis was substantiated.

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