Ryabokon' O. Clinical-pathogenetic of immune and neuroendocrinal changes and their medicamental correction at chronic hepatitis C

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0506U000719

Applicant for

Specialization

  • 14.01.13 - Інфекційні хвороби

21-12-2006

Specialized Academic Board

Д 26.614.01

State Institution "The L.V. Gromashevsky Institute of epidemiology and infectious diseases of NAMS” of Ukraine"

Essay

The results of the researches devoted to the study of clinic-pathogenetic role of immune and neuro-endocrinal changes in patients with chronic hepatitis C are represented in the theses. The immuno-neuroendocrinal concept of chronic hepatitis C progress is worked out on the basis of immune and neuro-endocrinal status complex study. Criteria non invasion estimations of liver fibrosis progressing in patients with chronic hepatitis C are worked out. Immuno-neuroendocrinal criteria of interferon therapy efficiency prognosis in patient with a chronic hepatitis C are proposed. Interferon therapy optimization by the combination with ursodeoxy-cholic acid for the patients with lasting harmful working conditions at industrial enterprises is proved.

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