Filchakov F. Initiation, potentiation and transfer of anti-tumor immune reactions in malignancies (experimental and clinical-and-immunological study)

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0507U000322

Thesis Registration Form

0507U000322.pdf

Applicant for

Specialization

  • 14.01.07 - Онкологія

16-05-2007

Specialized Academic Board

Д26.560.01

Essay

The thesis is devoted to the issues of increase of the efficacy of the treatment of cancer patients by the development of new and improvement of the existing (thymic preparations,alfa-interferon, low molecular extracts of lymphocytes, transfer factor) adjuvant methods of biotherapy. Methodical and practical approaches to simultaneous use of thymic preparations and alfa-interferon in the immunotherapy are experimentally grounded. The technology of in vitro generation of activated lymphoid cells from regional lymph nodes of cancer patients for adoptive immunotherapy has been developed. Principles of the combined biotherapy using thymic preparations, alfa-interferon and autologous lymphocytes with generated in vitro cytotoxic activity has been developed. The efficacy of each of the developed and improved methods of immunotherapy has been analyzed. Based on experimental development of the technology for receiving of tumor-specific transfer factor and determination of its anti-tumor effect the expediency for use of this trend of biotherapy for the improvement of the treatment efficacy in cancer patients has been grounded

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Files

Filchakov.F.V. aref.doc

Диссертация--РОЗДІЛ 1ОФИЦ.doc

Диссертация--РОЗДІЛ 2 ОФИЦ.doc

Диссертация--РОЗДІЛ 3 ОФИЦ.doc

Диссертация--РОЗДІЛ 4 ОФИЦ.doc

Диссертация--РОЗДІЛ 5 ОФИЦ.doc

Диссертация--РОЗДІЛ 6 ОФИЦ.doc

Диссертация--РОЗДІЛ 7 ОФИЦ.doc

Диссертация--Рис 3.25.doc

Диссертация--Рис.3.11.doc

Диссертация--СПИСОК ОФИЦ.doc

Диссертация--ТИТУЛ ОФИЦ.doc

Диссертация--Табл.3.2.doc

Диссертация--Табл.4.11.doc

Диссертация--Табл.6.8..doc

Диссертация--табл.6.2.doc

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