Kurchenko A. Atopic dermatitis: the characteristic of alteration in the systemic and local immunity properties

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0508U000154

Applicant for

Specialization

  • 14.03.08 - Імунологія та алергологія

06-03-2008

Specialized Academic Board

Д 26.003.02

Essay

The results show that in vitro the mononuclear cells of blood of the IgE-independent AD were revealed itself with reduced capacity for IL-5, IL-12 and, especially, IFN-, TNF- production. At the local level of immune response, in skin, the differences between clinical forms of AD were revealed itself with reduction in numbers of CD80+, CD86+, HLA-DR+ and CD25+cells in the dermal infiltrates of IgE- independent AD.

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