Gudaryan O. Ground of the differentiated methods of treatment of generalized parodontitis at diabetes of 2 type

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0508U000440

Applicant for

Specialization

  • 14.01.22 - Стоматологія

23-06-2008

Specialized Academic Board

Д44.601.01

Essay

Dissertation is devoted to the decision of problem of features of etiology, pathogenesis, clinical and treatment of generalized parodontitis at patients with diabetes of 2 type, by realization of positions of the developed conceptions of pathogenesis and criteria of origin and prognostication of a different display of inflammatory-destructive process in parodont. In dissertation, on the basis a lot of researches certain structure of microbiocenosis of parodontal tissue, set immune violations, state of exchange of lipids of whey of blood and processes of bone remodelation at different clinical displays of generalized parodontitis at diabetes 2 type. On the basis of the got results the differentiated medical and prophylactic methods of complex treatment of different variants of display of pathological process in parodont are scientifically grounded and approved in a clinic. In quality the criteria of objective estimation of the clinical state of parodontal tissue and conducted treatment, further prognosis of his ends in remote terms it is recom-mended to take into account not only clinical and X - ray information but also expedience of analysis of dynamics of levels of maintenance of sICAM-1 (CD54+) in the whey of blood is shown, and also concentra-tions in the unstimulated saliva IL-1B.

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