Kotova N. Health of the Children Born to HIV-infected Mothers and Protocol of Their Medical Management

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0508U000512

Thesis Registration Form

0508U000512.pdf

Applicant for

Specialization

  • 14.01.10 - Педіатрія

23-09-2008

Specialized Academic Board

Д 41.600.02

Odessa National Medical University

Essay

Dissertation covers approach to medical management of children born to HIV-infected women. Protocol was done on the base of the complex evaluation of the health of children born to HIV-infected mothers. Association between risk factors influence on HIV transmission was studied in 606 children born to HIV-infected mothers. Growth, psycho-motor development, mortality and morbidity of HIV-exposed newborns and uninfected infants were observed and compared. Clinical symptoms and laboratory data were evaluated from diagnostic eeffectiveness point of view. Evaluation of effectiveness and safety of measures of prevention was done in dissertation. Prominent bioethical problems in medical management of children born to HIV-infected women were found. Algorithm of HIV diagnostic in children born to HIV-infected mothers was created. It consists of 3 groups of measures including prevention, diagnostics and counselling. We clarified differential approach to complex medical care of newborns and infants.

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