. Object of the study: clinic-laboratory and anthropogenesis aspects of occurrence and current bronchial asthma Purpose of the study: To establish laws of occurrence and feature of current bronchial asthma at schoolboys of different age and a floor living in city and a countryside of Podolsk region of Ukraine, and also on the basis of the analysis of features sexual, anthropometric, somatotypology, and dermatoglyphics parameters to develop prognostic mathematical models of an opportunity of its development for use of preventive actions in groups of the raised risk of development of disease Methods of the investigation: clinical-instrumental, immunologic, allergological, anthropometric, somatotypological, dermatoglyphics, mathematical,statistical method. Theoretical and practical results: Prevalence of the cores clinical attributes of disease and feature of current of a bronchial asthma at city and rural children of school age of Podolsk region of Ukraine is established. The most informative criteria аtopic anomalies of the constitution and triggers factors which promote clinical displays of illness and its early formation are allocated. By means of the analysis аntropogenetics parameters of children healthy and sick of asthma ascertaining and prognostic factors are opened and discriminant models of risk of development of disease that allows to develop welltimed preventive actions are developed. It is established, that for children of 7-15 years living in territory of Podolsk region of Ukraine, characteristic there is an influence of many, as internal and external, risk factors of develop-ment of the bronchial asthma among which the most important are genetic factors which together with adverse current of pregnancy and sorts, infectious agents lead to formation so-called аtopy to anomaly of the constitution. At teenage age there is a change of risk factors - on the foreground there are not infectious agents, physical and psychoemotional loadings. Strengthen and provoke development disease such factors as, alow material standard of living, stressful situations. It is established that at teenagers the bronchial asthma has classical current whereas at children of 7-12 years in clinic of disease the high percent of whistling noisy breath is still kept. The author was the first to detect the fact that teen-agers and children of different sexes suffering from bronchial asthma have “diathesis” constitutional types, which are characterized by different-directed mutations of overall and longitudinal sizes of body; magnitude of distant epiphysis, enfolding body sizes, cellulocutaneous folds thickness. The gained results confirmed the value of distinguishing of “dermatoglyphical types” for study of individual and typological peculiarities of the bronchial asthma origin. Basing on the anthropogenetic research, the discriminant models of origin of the bronchial asthma among the urban and rural children and teenagers of Podolian region of Ukraine were elaborated for the first time. Novelty: - the first time features of current BA, prevalence of the basic clinical attributes and risk factors of development BA at children of different school age living in territory of Podolsk region are studied, was the first to detect the fact that children and teen-agers of different sexes suffering from BA have “diathesis” constitutional types, which are characterized by different-directed mutations of overall and longitudinal sizes of body; enfolding body sizes, cellulocutaneous folds thickness. The gained results confirmed the value of distinguishing of “dermatoglyphical types” for study of individual and typological peculiarities of the bronchial asthma origin. Degree of introduction: on the materials of the research, methodological recommendations “Forecasting of risk of development bronchial asthma at children and teenagers, by means of genotypic and phenotypic markers” were published; they were approved by the Ukrainian Research Centre of Scientific Medical Information and Patenting-Licensing Work Ministry of Health of Ukraine and agreedby the director of the Department of motherhood, the childhood and the sanatorium help of the Ministry of Health of Ukraine by V.V.Bondarenko (Kiev, 2008). Results of researches were introduced into the work of some children's medical establishments of Ukraine: a regional children's hospital of Vinnitsa, of Kirovograd, Odessa, municipal hospitals and out-patient departments of Vinnitsa and Vinnitsa, Odessa, Khmelnitskiy, Kiev areas. Results of the researches, etiologies concerning questions, features of clinical current, diagnostics, are used at carrying out of pedagogical process on faculties of pediatrics, family medicine and therapy of Vinnitsa national medical university by it. N.I. Pirogova. Sphere of application: medicine, paediatrics.
