Sotskaya Y. Clinical-pathogenetical peculiarities, treatment and medical rehabilitation of patients with the chronic uncalculosis cholecystitis, that combined with chronic viral hepatitis C with minimal activity on a background secondary immunodeficien?cy states

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0509U000365

Applicant for

Specialization

  • 14.01.02 - Внутрішні хвороби

05-06-2009

Specialized Academic Board

Д 29.600.01

Essay

In the dissertation were summarized facts of clinical-laboratory investigation 556 patients with the chronic pathology of the hepatobiliary system (HBS), what including 388 persons - with diagnosis chronic uncalculosis cholecystitis (CUC), that combined with chronic viral hepatitis C (CVHC) minimal activity (MA) on a background secondary immunodeficien?cy states (SIS) and with CUC without CVHC 168 persons from 18 to 59 years old. The role of immunologic, metabolic and microcirculations changes in the acute stage of pathologic process in gallbladder (GB) and hepar were study. Discove interaction between increasing maintenance proinflammatory cytokines (IL-1, TNF) and concentrations of middle molecules from one side and presence microcirculations changes, in the whole pathologic process in the HBS. Pathogenetic basic using remedies's combination lapherobion and polioxydonium and essential phospholipids (livolin, livenciale) in the complex therapy of patients with the CUC, that combined with CVHC with MA on a background SIS. Accelerating of restore immunologic and biochemistry indexes, what develop in the clinic plan by achicevement of resilient remission of disease. For preventive development acute stage of pathologic process in HBS conducting medical rehabilitation with use native hepatoprotector antral and phytopreparations (artichol, artichoke extract-Zdorovye).

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