Mamenko M. The scientific grounds and development of the program of monitoring, prophylaxis and treatment of the iodine and iron deficiency disorders in children.

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0509U000445

Applicant for

Specialization

  • 14.01.10 - Педіатрія

23-06-2009

Specialized Academic Board

Д 26.553.01

SI «Institute of Pediatrics, Obstetrics and Gynecology named academician O. M. Lukyanovaya NAMS of Ukraine»

Essay

The school-based 30-cluster survey in children 6-12-y-old of Luhansk Region was conducted. The existence of the iodine deficiency disorders and iron deficient anemia was proved to be the health and social problem in the region. It was demonstrated that the deficiency of the iodine and iron is the main etiological factor in the genesis of goiter and anemia in children and the effects of pollution are secondary. It was proved that the frequency of goiter and anemia becomes higher by age. It was found out the high level of minimal hypothalamic-thyroid dysfunction in children at the region. It was proved that hypothalamic-thyroid dysfunction is closely connected with iron deficiency. The new coefficients for evaluation of the goiter rate and for monitoring of the thyroid volumes under the treatment were created. The high efficiency of the iodine supplementation at the region with mild level of iodine deficiency and grate amount of endocrine disruptors was proved. The conclusion of the necessity of the iron supplementation to improve the efficiency of the iodine treatment of the endemic goiter was made. The regional model of iodine deficiency prevention program was created. The system of the assistance at the decisions' receiving in medical and social monitoring of children with iodine deficiency disorders was developed.

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