Samarin D. Clinical peculiarities of HIV-infection, the functional condition of lymphocytes and criteria of the beginning of ART-therapy in perinatally infected children

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0509U000455

Applicant for

Specialization

  • 14.01.13 - Інфекційні хвороби

25-06-2009

Specialized Academic Board

Д 26.614.01

State Institution "The L.V. Gromashevsky Institute of epidemiology and infectious diseases of NAMS” of Ukraine"

Essay

Anamnestic data, clinical manifestations, levels of the basic populations and subpopulations of lymphocytes, functional state of T-helpers in children born from a HIV-positive of mothers was studied. It is proved, that changes of functional condition of T-lymphocytes forestall development of clinical manifestations, depression of T-helpers levels in perinatally infected children. It is defined, that to-infections of HIV-positive children at III-IV clinical stages of HIV-infection, HSV that CMV lead to disturbance of T-helpers functional condition, in particular, balance of system T-helpers 1 and 2 types.

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