Sydorchuk L. Complex treatment of patients with arterial hypertension dependently on genes polymorphisms

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0510U000100

Applicant for

Specialization

  • 14.01.11 - Кардіологія

22-01-2010

Specialized Academic Board

Д 64.600.04

Essay

The thesis is dedicated to the problem of improvement of prophylaxis and treatment of patients with essential arterial hypertension dependently on genes polymorphisms ACE (I/D), AGTR1 (A1166C), eNOS (T894G), PPAR-gamma2 (Pro12Ala) and ADRB1 (Arg389Gly). The sensitivity scheme to antihypertensive first line drugs dependently on genotype of analyzed genes was created, individualized pharmacogenetically determined treatment correction was performed. Results - improvement of treatment efficacy; branch - medicine.

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