Britsun V. Transformations of 2-Acylthioacetamides to the Derivatives of Nitrogen-Containing Heterocycles

The dissertation is devoted to the development of efficient methods for nitrogen- and sulfurcontaining heterosystems formation on the base of 2-acylthiocetamides transformations. Some of these systems are new. The systematic investigation of 2-acylthioacetamides properties and reactivity was conducted: acidity, kето-enole-enthiolic tautomerism, autocondensations and regio-selectivity of their heterocyclizations with nitrogen-containing 1,2- and 1,3-dinucleophilic, 1-electrophil-3-nucleophilic and 1,2-, 1,3-dielectrophilic reagents with further annelation of the transformation products to the condensed polycyclic nitrogen- and sulfur-containing hetero-systems, also to the establishment of these processes regularity .