Object: pathology of meniscus at dysplastic knee joint. The aim: to prove the meniscogenic syndrome caused by heredity as nosological form due to clinical, biomechanical and theoretical methods and to work out the criteria of diagnostics and treatment. Methods: clinical, roentgenological, arthropneumographical, MRI, biomechanical, morphological, statistical, informational, methodology of systematic approach and conception modeling. At the first time the conception of meniscus pathology was worked out and proved from the sight of orthopaedic arthrology. Three types of meniscus pathology were dedicated depending on its genesis - dysplastic, traumatic, pathical. At the first time the conception of meniscogenic syndrome caused by heredity was worked out. It allowed to unite into homogeneous group different signs and symptoms of knee joint pathology with one common causal factor - genes determinated anomalies of meniscus and knee joint. At the first time meniscogenic syndrome caused by heredity was proved as nosologic form of dysplastic pathology of knee joint. The direct meniscogenic syndrome, caused by heredity was revealed. The cause of meniscus destruction is its abnormality. Another syndrome is indirect, at this situation destruction is caused by force of abnormal bone tissue of knee joint. At the first time the classification of meniscogenic syndrome caused by heredity was worked out. It is based on many factors and clinical symptoms. The reasons and types of meniscogenic knee arthritis were determined - direct and indirect. The cause of direct meniscogenic knee arthritis is abnormality of meniscus structure, the cause of indirect meniscogenic arthritis is destruction of meniscus by abnormal bones. At the first time we showed the influence of load on the meniscus, which caused the development of degenerative changes due to improved mathematical model of varus deformity. It was revealed that in patients with meniscogenic syndrome, caused by heredity, arthritis changes appear at the second to the fourth stages after pericapsular resection of traumatic meniscus. 94,7 % patients do not demonstrate the development of arthritis changes at long term follow up period. At the first time the scheme of diagnostics of meniscogenic syndrome was worked out, it allowed us to specify its criterias and the character of dysplastic changes in knee joint. At the first time the tactics of surgical treatment was worked out, it defines the volume of operation depending on the etiology, pathogenesis and clinical symptoms. It was established that meniscogenic syndrome caused by heredity dominate under traumatic and pathic pathology of meniscus. The new effective methods of conservative and surgical treatment of knee joint arthritis were transferred to the System of health protection. Theoretical methods can be used in orthopaedics for integrative studies. Selection of tree types of meniscus pathology can improve the diagnostics, treatment it will promote the prophylaxis of dysplasic knee arthritis. The conception of meniscogenic syndrome which was worked out allowed us to examine the meniscus pathology together with other elements of knee joint. It will promote to set a correct diagnosis and to make correct surgical procedure. The knowledge of load distribution in the knee joint can prove the necessarily of roentgenological examination of knee joint in the AP straight position. Suggested algorithm of diagnostics can help us to determine the right diagnosis of meniscogenic syndrome caused by heredity and to promote the right choice of surgical treatment taking into consideration the character of pathological changes in the joint. The tactics of surgical treatment which was worked out allowed us to increase the quality of treatment and to prevent the development of knee arthritis. It will improve the quality of life and work capacity. The results of investigation were introduced in to clinical practice of Sytenko institute of Spine and Joint Pathology, National academy of Medical sciences of Ukraine, Kharkov Regional Clinical Traumatological Hospital, Volisnsky Regional Clinical Hospital , Nikolaev Clinical Hospital №3, Zakarpatsky Regional Clinical Hospital . Traumatology and orthopaedics.
