Glazunov O. Integrated treatment and prevention of common dental diseases among workers of the mining industry

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0513U000974

Applicant for

Specialization

  • 14.01.22 - Стоматологія

23-09-2013

Specialized Academic Board

Д 41.563.01

State Establishment «Institute of Stomatology and Maxillofacial Surgery National Academy of Medical Sciences of Ukraine"

Essay

Epidemiological survey of miners city Krivoy Rog showed a constant increase in the prevalence of pathology in periodontal tissues, hard tissues of teeth, oral liquid, blood serum and bone metabolism with increasing underground work experience, and the combination of occupational diseases (dust bronchitis and vibration disease). In the simulation of an experiment in terms of mining production shown the reduce of nonspecific resistance of animals, a material breach of biochemical processes and reduce of antimicrobial protection in the mouth, the growth of pathogenic organisms and higher levels of calcium, magnesium and reduction of inorganic phosphates in oral liquid, increased MDA, decreased activity of catalase and IT growth of OPA. The use of adaptogens, vitamins and minerals, lecithin, mouthrinse helped the normalization of these parameters. Use within 2 years of a certain scheme developed by the therapeutic and preventive sector, acting on the various level of organism protection at different hierarchical levels stabilized dental status, reduced in oral liquid and blood serum urease activity of miners, MDA content, total proteolytic activity, ALT and AST, the interval of pH fluctuations, increased activity of lysozyme, catalase, trypsin inhibitor content, normalized charge state of buccal epithelial cells and functional status of microcapilar ductus of periodontal tissues on a background of constant exposure risk factors for mining production.

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