Iskra R. Biochemical processes in animal organism by the action of various compounds of chromium(III).

Object of study - biochemical processes in animals by the action of the compounds Cr(III). The purpose of research - find out characteristics of biochemical processes in animals by the action of Cr (III) and develop methods of correction of metabolic disorders using its mineral and organic compounds. Methods - biochemical (determination of enzyme substrates and content), physiology (the study of the morphological parameters of blood, the intensity of growth of animals), immunological (determination of cellular and humoral immunity), chromatographic (determination of vitamins and protein fractions) statistics. The results - we investigated the biochemical processes in rats, rabbits and pigs under the influence of mineral and organic compounds of chromium(III), including compounds obtained using nano-and biotechnology. Research has elucidated the mechanisms of metabolism of Cr (III) in the animals according to their physiological status and different periods of ontogenesis: pregnancy, childbirth, lactation and weaning. The formation of violations of biochemical processes of metabolism in animals with a deficit of chromium (III) in the diet was experimentally confirmed. It was elucidated that chromium chloride and chromium citrate as biocomplexes of chromium yeast Saccharomyces cerevisiae show dose-dependent stimulating effect on metabolic processes in animals, characterized by increased intensity of carbohydrate, protein and lipid metabolism, antioxidant function, NO-synthase, endocrine and immune systems. The metabolically effective amounts of chromium (III) compounds , which can be used as the recommended dose intensities in order to activate metabolism and prevent trace elements deficiency in the body, were established for rats, rabbits and pigs.