Sukhanova L. Tuberculosis of the respiratory organs, combined with connective tissue dysplasia: pathogenesis, diagnosis, clinical picture, clinical course, and after-effects of a disease

Object of study: tuberculosis of th respiratory organs; aims to improve the efficiency of TB diagnostics of the respiratory system in conjunction with connective tissue dysplasia, develop diagnostic criteria, study the pathogenesis, diagnostics, clinic, course, prognosis and outcomes; research methods: clinical, radiological, laboratory and statistics; novelty: for the first time expanded and scientifically substantiated new links of the pathogenesis of respiratory tuberculosis in combination with systemic connective tissue dysplasia; specific features of its course, prognosis and outcomes in depending on the presence of connective tissue dysplasia; the radiographic features and criteria of systemic dysplasia of connective tissue of the lungs, calculated the coefficient of reduction of the area of the lung and the classification of the degree of dysplasia of connective tissue of the lungs; studied morphological peculiarities of lung tissue; the state of local and General immunity; the state of metabolism; the content of elastase, atypical forms of collagen and essential micro - and macroelements; installed according to factor analysis 8 the main factors in the diagnosis of tuberculosis of respiratory organs in combined with connective tissue dysplasia, confirmed using discriminant analysis the correct division of the patients into groups and subgroups. Field of application - medicine.