Shepitko K. Morphofunctional characteristic of rat normal small intestine wall and after administration of cryopreserved placenta concomitant with aseptic peritoneal inflammation

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0515U000956

Applicant for

Specialization

  • 14.03.09 - Гістологія, цитологія, ембріологія

03-12-2015

Specialized Academic Board

Д 26.000.06

Essay

For the first time in this dissertation established single subcutaneous administration of cryopreserved placenta is implemented through the complex mechanisms of its bioactive substances' interaction with structural and functional profile of small intestine, manifested by the enlargement of small intestine wall, caused by the swelling of submucous layer with maximum values of the rates on day 5-7. The recovery of the studied indices to the rates of intact group has been noted on day 10 of the experiment. The corrective role of single subcutaneous administration of cryopreserved placenta concomitant with simulated acute aseptic peritoneal inflammation was evident by the fact that the recovery of all indices to the values of the intact group was noted on day 10-14, reducing the manifestations of inflammation at the stages of alteration and exudation, intensifying the reparative processes and shortening the time of the recovery of small intestine structural components, affected by the inflammatory process on day 5-7.

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