Astapenko O. Development and justification of the application of constructions made from biodegradable material with bioactive action in reconstructive surgery of maxillofacial area (experimentally-clinical research)

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0516U000114

Thesis Registration Form

0516U000114.pdf

Applicant for

Specialization

  • 14.01.22 - Стоматологія

21-01-2016

Specialized Academic Board

Д 26.003.05

Bogomolets National Medical University, Ministry of Health of Ukraine

Essay

The dynamics of bone injuries of facial skull and the spectrum of metal osteosynthesis complications were studied by means of the retrospective analysis of archival material from the period 2004 to 2014. The results of the study were the basis for finding ways to obtain the material without metal defect, from which it would be possible to make fixator in the form of plates and screws for the osteosynthesis in maxillofacial region. It was developed biodegradable material of bioactive action (EPU-GAP-LEV) based on polyurethane composition which contains 20 % hydroxyapatite, and 6 % levamisole for osteosynthesis fixator. Results of experimental studies were the basis for clinical and radiographic studies. It was proved effectiveness of EPU-GAP-LEV fixators for osteosynthesis in the treatment of the patients with fractures and deformations of facial skull.

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