Lashkul D. Clinical and pathogenetic aspects of diagnosis, treatment and prediction of ischemic chronic heart failure in patients with renal dysfunction

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0517U000542

Thesis Registration Form

0517U000542.pdf

Applicant for

Specialization

  • 14.01.11 - Кардіологія

26-06-2017

Specialized Academic Board

Д.17.600.02

Essay

The dissertation presents a solution for the problem of modern cardiology to improving diagnosis, treatment and prognosis of ischemic chronic heart failure in patients with renal dysfunction. The peculiarities of clinical course, variability of daily blood pressure, structural and functional remodeling and diastolic heart function, the state of the extracellular matrix, biomechanical stress, inflammation, cardiovascular remodeling and kidney damage in patients with ischemic heart failure with renal dysfunction. Established independent predictors of adverse cardiovascular events (sudden cardiac death, hospitalization for decompensated heart failure, atherothrombotic events) in patients with ischemic heart failure. It is proved that the addition of statins, trimetazidine, nitrates to optimal drug therapy reduces the relative risk of cumulative outcome in patients with ischemic heart failure with renal dysfunction.

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Files

Лашкул Д.А._Автореферат.doc

Лашкул Д.А._Дисертація.doc

Лашкул Д.А._Дисертація.doc

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