Kharchenko K. The role of cytoreductive surgery in combined treatment of recurrent ovarian cancer

Clinical manifestations, diagnostics, course of ovarian cancer recurrence depending on treatment tactics and peculiar properties of surgery are described in details bycurrent dissertation. For the first time, the peritoneum dividing into six divisions was substantiated and a universal scale for the assessment of peritoneal carcinomatosis was proposed (CASPeR). CASPeR takes into account both anatomical and surgical aspects, that distinguishes it favorably from existing scales. It may be used as a predictor of the optimal cytoreduction. For the first time, the features of surgical interventions in the localization of recurrence in the pelvic region were described in detail taking into account the previous surgeries and oncological radicalism.A method of prosthetics of the external iliac artery using an autotransplant and a method of complex treatment of ovarian cancer recurrence have been developed. Also, it was developed scale (SeCRiSROC) for the risk assessment of patient undergoing secondary surgical cytoreduction with algorithmfor its further application in clinical practice. It allows to justify performance or refusal from surgery for such patients.