Panasyuk O. Mixture infections in inflammatory diseases of the nervous system: clinic, diagnosis, treatment

The dissertation is devoted to the solution of the problem of clinical diagnosis, diagnosis and treatment of mixed infections in inflammatory diseases of the nervous system. The description of nosological forms, course, general clinical manifestations of viral-viral, viral-bacterial mixt-infections is presented. The immunological parameters, spectrum and levels of serum cytokines and CSF in patients with mono-and myxo-infections in two nosological forms AE and SEM are described. The effectiveness of four treatment regimens for patients with viral-viral, viral-bacterial infections has been analyzed. The dynamics of changes in levels of proinflammatory cytokines (IFN-α, IFN-γ, FNТ-α, IL-1β, IL-2, IL-6) in CSF after the first intracerebral to inject of dexamethasone is presented. The results of a long (3–5 years) catamnestic observation of patients after the main course of therapy are presented. The evaluation of the effectiveness of antirecession therapy and the effects of inflammatory diseases of the nervous system is given.