The dissertation thesis presents the research of the current scientific problem of developing theoretical and methodological, conceptual foundations, organizational and methodological approaches to forming the government, science and business interaction. The concept is studied in the process of national economy innovative development in the transition to the structural and functional organization of NIS based on the "triple helix "model.
The thesis generalized and developed the theoretical basis of national economy innovation development by highlighting a chain of its key concepts in the dominant paradigms and morphological features of Ukrainian NIS evolution at the level of its structural and systemic interaction. A theoretical approach to interpreting the concept of the government, science and business interrelationbased on the "triple helix" model of NIS type from the perspective of the physical economyconcept was developed. Concurrence of system properties and attributes of the government, science and business functional elements interrelationto systems' criteria with automatic control was revealed.
The methodology for studying the government, science and business interrelationin innovative economy development was formed. It was based on the principles formulated in the thesis, through a methodological synthesis of the fundamental principles of marginalist and institutional trends, schools and concepts, the theory of economic development, the idea of innovative development of an entrepreneurial society, synergetics. The methodological approach to increasing the synergy of government, science and business interrelation was improved, based on the use of a multilevel system of indicators of the Global Innovation Index, Spearman's nonparametric correlation coefficient and impulse relationships interpretation of indicators. The methodological approach to the optimization of the instruments of state regulation of the national economy innovative development using the automata theory and Boolean algebra was improved.
A complex of factors that define the government's structural and functional organization, science and business interrelationin the process of national economy innovative development was determined. The NIS profiles were built following their different models. The scientific approach to ensuring the conditions for the accelerated transition of Ukraine to the government, science, and business interrelation according to the "triple helix" model, represented by four main trajectories, including the domestic NIS's morphological features, waselaborated. The concept of the government, science and business interrelationin the transition of the innovative development of the Ukrainian economy to the "triple helix" model, based on the postulate formulated in the dissertation thesis and detailed at five levels: methodological, goal-setting, methodological, instrumental, organizational, was proposed.
The systemic problems of national economy innovative development were diagnosed. The scientific approach to ensure the conditions for Ukraine's transition to economy innovative development based on the "triple helix" model, represented by four main trajectories (decentralization of management of innovation processes, diversification of their financial support, the leading role of universities, a network organization of relationships), taking into account morphological features of the national NIS was developed. The directions for the government, science and businessinterrelation process (institutional development of the innovation sphere, the result of internal interactions, development of external scientific communications, development of forms of financial interaction), which take into account the combined effects formed due to the relationship between its elements, were formulated. The set of strategic guidelines for the transformation process of the government, science and businessinter relation, aimed at the institutional attractors' formation transition of the Ukrainian NIS's structural and functional organization in the "triple helix" model, was formed.
