Pasiieshvili T. Pathogenetic and prognostic role of biomarkers of systemic inflammation and nonspecific protection in the development and course of gastroesophageal reflux disease in young patients with autoimmune thyroiditis

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0521U101941

Thesis Registration Form

0521U101941.pdf

Applicant for

Specialization

  • 14.01.02 - Внутрішні хвороби

28-09-2021

Specialized Academic Board

Д 64.051.33

V.N. Karazin Kharkiv National University

Essay

The work presents a theoretical substantiation and solution of an problem of modern medicine - determination of the features of the combined course of gastroesophageal reflux disease and autoimmune thyroiditis in young people, based on a comprehensive assessment of disorders from the immune status, indicators of the antioxidant system, autoimmune changes and pathomorphological manifestations. Based on the definition of the pathogenetic role of biomarkers of systemic inflammation, the activity of antioxidant enzymes and factors that modulate oxidative stress, conceptual measures have been developed aimed at improving the early diagnosis and prediction of the course of gastroesophageal reflux disease in combination with autoimmune thyroiditis in young people.

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Files

autoreferat-aref.pdf

dis.pdf

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