Sidorov A. Adherence to basis therapy of COPD and its impact on clinical and pharmacoeconomic parameters

Українська версія

Thesis for the degree of Doctor of Philosophy (PhD)

State registration number

0820U000213

Applicant for

Specialization

  • 222 - Медицина

24-12-2020

Specialized Academic Board

ДФ 05.600.008

Essay

According to the results of the conducted study with 156 patients enrolled the adherence to treatment increased from (44.41 ± 1.07) to (75.21 ± 0.78) %, i.e. by 30.8 %. It was demonstrated in Ukraine firstly. It was established for the first time that main factor which has influence on adherence to treatment is interaction "doctor-patient". For the first time in Ukraine thanks to activities for adherence to treatment increase the intensity of COPD symptoms was diminished (according to CAT and mMRC scores), the quantity and duration of COPD exacerbations were decreased, some spirometry parameters were increased. Moreover, the costs for hospitalisations due to COPD exacerbations and annual costs for COPD treatment decreased significantly.

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