Shymova A. Nutritional disorders among end-stage renal disease patients treated with peritoneal dialysis.

Українська версія

Thesis for the degree of Doctor of Philosophy (PhD)

State registration number


Applicant for


  • 222 - Медицина


Specialized Academic Board

ДФ 26.565.001

State Institution "Institute of Nephrology NAMS of Ukraine"


Nutritional disorders are found among 33–64 % of patients treated by PD and are of great prognostic importance for the morbidity and survival rates of these patients. The aim of the dissertation was to increase the treatment effectiveness of nutritional disorders in patient’s treated by continuous ambulatory peritoneal dialysis (CAPD) by complex treatment with levocarnitine and intraperitoneal solutions with amino acids. According to the analysis results, it was registered that during the treatment we have got a credible positive result of complex therapy with the use of L-carnitine and intraperitoneal fluid with amino acids. It has been proved that more than half (55,2 %) of end-stage renal disease patients treated with CAPD have disturbance of nutritional status. It has been shown that nutrition disorders with the decrease of skeletal muscle mass while saving fat mass can be diagnosed with the help of bioimpedance measurement. It has been established that the degrees of severity on nutritional disorders in PD-patients with high indicators of oxidative stress. Also, it was shown that peritoneal dialysis patients were registered to have low overall life quality index.


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