Kramarenko D. Morphofunctional characteristics of rats’ major salivary glands in a norm and after methacrylate exposure

Salivary glands should compensatory increase the secretory activity to ensure adequate hydration of the oral mucosa. The population of the planet increasingly needs prosthetics, given the general trend towards its aging. It is proved that when using prostheses, patients often have complaints of xerostomia. Despite the disadvantages, methacrylates have found wide application in dentistry as a basis for dentures, due to its high performance. Toxic effect can be caused by methyl ester of methacrylic acid as a component of the base of the prosthesis. Many studies have examined the effect of methacrylate monomer on the oral mucosa, but there are not numerous studies on the condition of organs located outside the oral cavity after exposure to methacrylic acid ester. The purpose of the work was to study morphofunctional changes in the submandibular salivary glands of rats in a norm and after exposure to 1 % methacrylic acid ester.