The thesis is devoted to toxicological assessment of pesticides and hygienic assessment of the impact of pesticide formulations on professional contingents, populations and environmental objects when used in the system of chemical protection of potatoes. The protection system involves the use of Cruiser 600 FS, Uniform 446 SE, SE, Artist 41.5, WG, Colt Power, VG, Fielder 69, VG, Zorvek Incantia, SE and Reglon Forte 200 SL, RK at the different culture growing stages.
Toxicological evaluation of Cruiser 600 FS, Uniform 446 SE, SE, Artist 41.5, WG, Colt Power, VG, Fielder 69, VG, Zorvek Inkantia, SE, Reglon Forte 200 SL, LCD and their active substances.
Based on the data analysis from official web-resources and literature sources, we have analyzed the toxic properties of the studied preparations and their active substances and found that the parameters of acute toxicity in accordance with DSanPiN 8.8.1.002-98 drugs Cruiser 600, FS, Fielder 69, VG, Zorvek Incantia, SE belong to the III class of danger (moderately dangerous), Uniform 446 SE, SE, Artist 41,5, WG, Colt Power, VG, Reglon Forte 200 SL, RK - to the II class of danger (dangerous), in all cases limiting criterion - acute inhalation toxicity). Their active substances thiamethoxam, imidacloprid, famoxadone, oxathiapiproline belong to the III class of danger (moderately dangerous), azoxystrobin, metalaxyl-M, flufenacet, metribuzin, dimetomorph, mancozeb and diquat - to the II class of danger (danger), according to DSanPiN 8.8.1.002-98.
The sanitary and hygienic field studies of working conditions used in the industrial sector in the chemical protection system have been carried out and the possibility of acute toxic effects on workers working with the studied pesticides were predicted. We have assessed the risk of dangerous effects of the studied pesticide formulations on professional contingents in their complex and combined receipt and substantiated the regulations for the safe use of pesticides in the system of chemical protection of potatoes.
It has been established that in the real conditions of processing with preparations Cruiser 600 FS, Uniform 446 SE, SE, Artist 41,5, WG, Colt Power, VG, Fielder 69, VG, Zorvek Inkantia, SE, Reglon Forte 200 SL, RK and the maintenance of recommended agrotechnical and hygienic regulations for the safe use, air excess according to hygienic standards to the working area, soil and hygienic requirements are not violated from the standpoint of labor protection. It has shown that the hazard index (combined risk) in the consistent use of pesticides in the system of chemical protection of potatoes exceeds the allowable (> 1) and is 1,72 – 2,39, and the ways to reduce the occupational risk by justifying regulations for the safe use of pesticide formulations have been offered.
Prediction of the occurrence of acute toxic effects on workers have shown that the calculated values of KVDing (102,3 – 1646,1) for d.r. azoxystrobin, metalaxyl-M, imidacloprid, dimetomorph, famoxadone, oxathiapiproline, diquat were more than 100, which indicates a fairly high selectivity of their action. KVDing values, (14,7 – 61,6) of thiamethoxam, flufenacet, metribuzin, mancoceb ranged from 14,7 to 61,6, which indicates low selectivity of their action. The calculated values of KVDderm, for all d.r. in the r ange of 102,9 – 10288,1, which indicates a sufficiently high selectivity of their action (Table 2).
The obtained results indicate a fairly high probability of acute toxic effects when thiamethoxam, flufenacet, metribuzin, mancoceb enter the body of workers by inhalation. If the above active substances get through the skin, as well as other test substances through the skin and respiratory tract, the probability of acute toxic effects on agricultural workers is low.
