Kogan M. The diagnostic value of near-infrared transpalpebral transillumination in patients with eye injury

Українська версія

Thesis for the degree of Doctor of Philosophy (PhD)

State registration number

0821U101762

Applicant for

Specialization

  • 222 - Медицина

10-06-2021

Specialized Academic Board

ДФ 41.556.001

State Institution "The Filatov Institute of Eye Disease and Tissue Therapy of NAMS of Ukraine"

Essay

Object. Penetrating globe injury and contusion of the globe. Purpose. To improve the efficacy of diagnosis for trauma-related changes of the eye globe (blunt trauma, penetrating injury with/without intraocular foreign bodies) by using infrared transpalpebral transillumination. Methods. Infrared transillumination was performed in the experimental study. Visometry, biomicroscopy, ophthalmoscopy, infrared transpalpebral transillumination, X-ray examination with and without using the Komberg-Baltin prosthesis, ultrasound scanning of the anterior eye and posterior eye, ultrasound biometry were performed in the clinical study. Statistical analysis was performed using the software package Statistica 10.0. Scientific novelty. Scientific data on the direct relationship between the dimensions of the ciliary body structures and axial length in people with emmetropia, hyperopia, and myopia was upgraded. Thus, in patients with axial length ranging from 20 mm to 22.9 mm, 23 mm to 24.9 mm, and from 25 mm to 35 mm, pars plana width was 3.1 ± 0.7 mm, 4.1 ± 0.3 mm, and 5.0 ± 0.8 mm, respectively. It was found for the first time that, due to the absorption, reflection and refraction features of the near-infrared light (940 nm wavelength), infrared transpalpebral transillumination made it possible to visualize intraocular foreign bodies, independently on their nature, localized in the anterior segment of the eye with transpalpebral illumination, also in the presence of opaque media. It was found for the first time that the ciliary body pars plicata width was wider in patients with moderate and severe contusion of the eye as compared to fellow intact eyes, which may evidence the presence of post-traumatic ciliary body edema. Thus, the ciliary body pars plicata width in patients with contusion of the globe was 2.5 ± 0.1 mm vs. 2.0 ± 0.1 mm in fellow intact eyes. Practical value. Infrared transpalpebral transillumination was found to enable visualization of hard-to-reach structures of the ciliary body pars plicata and pars plana due to the absorption and transmission of infrared radiation with a wavelength of 940 nm. A new method of visualization of intraocular foreign bodies in the infrared range of the spectrum was developed, which allows non-invasive imaging of structures of the anterior segment of the eye (conjunctiva, cornea, limbal and paralimbal part, iris, ciliary body, lens) and intraocular foreign bodies relative to ciliary body structures. Using a developed method of infrared transpalpebral transillumination together with radiographic and ultrasonic methods of visualization increased the efficacy of intraocular foreign bodies detection in the anterior segment of the eye, in general, by 10% due to both increased detection of X-ray-negative and small (0,5-1 mm) intraocular foreign bodies. Infrared transpalpebral transillumination for the patients with contusion of the globe enabled noninvasive imaging the damage to the iris and the sclera (iridodialysis in the iris root area, tears of the pupillary margin, subconjunctival scleral ruptures) due to variations in absorption and transmission of the near-infrared light by these structures. The results of the work were introduced into the clinical practice of the Department of post-traumatic pathology of the eye of the State institution “The Filatov Institute of Eye Diseases and Tissue Therapy of the National Academy of Medical Sciences of Ukraine”, Odesa; surgical department № 2 of the municipal institution "Starobilsk District Territorial Medical Association", Starobilsk; clinical highly specialized center of eye microsurgery with a block of eye trauma and acute pathology of the visual organs of the Municipal non-profit company "The Pirogov Vinnytsia Regional Clinical Hospital of the Vinnytsia Regional Council", Vinnytsia. Scope. Medicine, ophthalmology.

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