Chereschyuk I. Rat liver histological and biochemical changes under the influence of pyrrole derivative and C60 fullerenes in settings of chemically induced colon cancer

Українська версія

Thesis for the degree of Doctor of Philosophy (PhD)

State registration number

0821U102316

Thesis Registration Form

0821U102316.pdf

Applicant for

Specialization

  • 091 - Біологія. Біологія

30-08-2021

Specialized Academic Board

ДФ 26.001.178

Taras Shevchenko National University of Kyiv

Essay

The research is dedicated to the study of new potential anticancer substances C60 fullerenes and pyrrole derivative (1-(4-Cl-benzyl)-3-chloro-4- CF3-phenylamino)-1H-pyrrole-2,5-dione (MI-1)) and their combinations‘ impact on liver under chemically induced colon cancer. The results of the study could contribute to clinical diagnostic criteria development for the assessment of therapeutic substances‘ toxicity . The study could be served as a part of preclinical trial of these compounds. The research topic is relevant because of urgent need of new effective and low-toxic anticancer drugs. According to the WHO data, colorectal cancer occupies the 3rd place in the number of cases and the 2nd place in mortality worldwide among gastrointestinal tumors.

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Files

autoreferat-АНОТАЦІЯ Черещук I.O..pdf

autoreferat-автореферат Давиденко Н. В.pdf

dis_Черещук І.О..pdf

акти впровадження Давиденко Н. В.pdf

дисертація Давиденко Н. В.pdf

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