Kozariichuk N. Peculiarities of morphogenesis and topography of the neuro-vascular and muscular structures of the organ of vision in the prenatal period of human ontogenesis

Українська версія

Thesis for the degree of Doctor of Philosophy (PhD)

State registration number

0821U102454

Applicant for

Specialization

  • 222 - Медицина

13-10-2021

Specialized Academic Board

ДФ 76.600.021

Bukovinian State Medical University

Essay

Preparations of 30 embryos, 30 prefetuses and 60 human fetuses were studied using a complex of morphological investigation methods to find out the peculiarities and chronological succession of the origin of rudiments, space-time dynamics of neurovascular and muscle structures formation of the organ of vision in human prenatal ontogenesis. The 4th week of IUD – the period of differentiation and organogenesis – and the 6th month of IUD, during which there is a nervous irregularity in the growth rate of the eyeball as well as in the size of the fossa, have been determined to be the critical periods of the development of the orbit and its structures. Mathematical functions that can serve as algorithmic variables of the software for computerized devices of the medical diagnostic imaging to detect abnormalities in the development of the fetal organ of visus are deduced for the first time. Three dimensional computer reconstructive models, which demonstrate dynamics of organogenesis and topographic-anatomic rearrangements of the orbit structures in the human prenatal ontogenesis, have been created.

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