Lahoda D. Adequate health care and prophylactic complex in patients with bronchial asthma on a small overweight or obesity.

Українська версія

Thesis for the degree of Doctor of Philosophy (PhD)

State registration number

0821U102471

Applicant for

Specialization

  • 222 - Медицина

19-10-2021

Specialized Academic Board

ДФ 64.600.041

Kharkiv National Medical University

Essay

The dissertation substantiates a complex of measures for the treatment and prevention of somatic diseases, namely, bronchial asthma (BA), in patients with overweight (OW) or obesity, which includes, in addition to standard recommendations, the administration of additional drugs of bacterial lysate and inosine pranobex in combination with recommendations for diet therapy, respiratory exercises (RE) and controlled dosage of physical activity (CDPA), which patients receive while studying at the Asthma School. For prospective cohort research tasks, the work consisted of two stages: stage 1 –the examination of 105 patients with BA – the formation of the main cohort group according to the criteria of inclusion / exclusion, “Patients with BA against the background of OW or obesity”, which included 75 patients, and a comparison group according to the inclusion / exclusion criteria, "Patients with BA against the background of normal body mass index (NBMI)", which included 30 patients. A control group included 20 somatically persons with NBMI to determine reference values of some indices. At the 2nd stage of the study, a treatment-and-prevention complex (TPC) was administered to the main cohort group of the 1st stage, which was divided into the main group – 30 patients, the comparison group – 30 patients, control group – 15 patients that refused the proposed TPC. For the first time Asthma School was introduced in the practical work of doctors, namely for the patients with frequent bacterial-viral infections with comorbid OW orobesity. The training program consisted of theoretical and practical training aimed atdeepening theoretical and practical knowledge of the disease in order to optimize asthma control in this cohort of patients.

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