Shostatska M. Peculiarities of the courseof acute intestinal infections which are caused by opportunisticmicroorganismsin elderly people

Українська версія

Thesis for the degree of Doctor of Philosophy (PhD)

State registration number

0823U100420

Applicant for

Specialization

  • 222 - Медицина

23-06-2023

Specialized Academic Board

ДФ 05.600.074

Vinnytsia National Pirogov Memorial Medical University

Essay

The dissertation research is devoted to solving the actual scientific and practical problem of modern medicine, which consists in determining the features of the course of acute intestinal infections caused by opportunistic microorganisms in the elderly and senile age. The purpose of thedissertationis to determinethefeatures of thecourseof acute intestinal infections caused by opportunistic microorganisms in the elderly and senile age, taking into account the leading etiological factor of the disease, the severity and diagnosed comorbid conditions of patients. As a result of the study, for the first time on the basis of the analysis of hematological integral indices in elderly and senile patients with AII caused by OM, it was possible to establish natural differences in the indicators of adaptive capabilities and reactivity of the body, taking into account the etiological factor of the pathological process. For the first time, the high prognostic value of determining comorbid conditions in elderly and senile patients in relation to the early diagnosis of the features of acute intestinal infection caused by OM. To determine the role of concomitant diseases diagnosed in elderly and senile patients with COVID-19, in relation to the features of the course of acute intestinal infection caused by OM. For the first time, the role of risk factors related to the course of COVID-19 in predicting the features of the course of acute intestinal infection caused by OM in elderly and senile patients with COVID-19 was determined. Comorbid conditions associated with higher chances of severe and complicated acute intestinal infection in elderly and senile patients with COVID-19 and acute intestinal infection due to OM, which require careful monitoring, are: the presence of values of the total result of the ABCD questionnaires of 5-6 points, the modified NEWS questionnaire ≥ 7 points, the severity index of COVID-19 ≥ 8 points.

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