Batiukh O. Predicting the influence of sleep disorders and anxiety on the development of cardiovascular diseases in patients with type 2 diabetes mellitus

The paper provides a theoretical generalization and solves the problem, which consisted in analyzing the relationships between anxiety, sleep quality, adherence to treatment and changes in blood pressure values during the day in patients with type 2 diabetes mellitus with the presence/absence of concomitant hypertension and differentiating the risk coefficients of these factors in order to determine strategies for early diagnosis and prevention of diseases. For the first time in Ukraine, the risk coefficients for anxiety levels, decreased adherence to treatment, increased sleep quality index, and abnormalities of daily blood pressure profile in patients with type 2 diabetes mellitus and hypertension were investigated using prognostic models of risk factors. The interrelationships and interactions between personal anxiety, compliance, sleep quality, daily blood pressure in patients with type 2 diabetes mellitus and arterial hypertension were studied and analyzed, and the significance of these indicators for the development of arterial hypertension in patients with type 2 diabetes mellitus was established. The prevalence of high anxiety (51,9 %), low adherence to treatment (46,2 %), poor sleep quality (80,8 %), and the prevalence of non-dipper blood pressure profile (46,2 %) in patients with type 2 diabetes mellitus and hypertension was found. In contrast, patients with type 2 diabetes mellitus without comorbidity showed significantly higher rates of average (with a tendency to high) anxiety (48,0 %), high adherence to treatment (44,0 %), and prevalence of a dipper BP profile (52,0 %), with a similar prevalence of poor sleep quality (72,0 %) compared to respondents with comorbidity.