Shesterina D. The effect of intermittent pneumatic compression on hemodynamics.

The aim of the reseach was to determine the individual features of the functioning of central and peripheral hemodynamics, heart rate variability under the influence of intermittent pneumatic compression (IPC) in healthy young men. To achieve the goal, the following tasks were set: 1. To investigate changes in the functional indicators of the cardiovascular system during the influence of intermittent pneumatic compression of the lower extremities and during the recovery period after it. 2. To establish the specifics of the impact of IPC on hemodynamics at different initial levels of autonomic tone in young men. 3. To find out the influence of IPC on peripheral hemodynamics depending on the level of blood filling of the lower extremities. 4. To compare changes in hemodynamics at different intensity levels of IPC. 5. To analyze the impact of IPC on the dynamics of blood pressure in persons with chronic venous insufficiency. The object of research was central and peripheral hemodynamics, heart rate variability, blood pressure in healthy young men and in people with chronic venous insufficiency. The subject of research was the effect of IPC on the characteristics of changes in the cardiovascular system in men, depending on the individual characteristics of the body. Research methods: electrocardiography, arterial measurements, tetrapolar rheography of the chest and lower extremities, statistical and spectral methods of heart rate variability, parametric and non-parametric statistical methods of processing research results. The scientific significance of the obtained results lies in the fact that the effectiveness of IPC with pressure of 40 mmHg due to the stabilization of blood pressure depending on the individual characteristics of the functioning of the autonomic nervous system has been established. It was found that in people with a sympathetic type of regulation, blood pressure maintenance is the result of complex neurohumoral interactions, and in men with a parasympathetic type - due to the vascular components of vessels of the 2nd order and capillaries, the values of which can be used for further recommendations in the prevention of vascular diseases and lymphadenopathy. It was shown that changes in hemodynamic parameters (heart rate, cardiac index, stroke index, total peripheral vascular 7 resistance) in response to the effect of IPC depend on the initial tone of the sympathetic and parasympathetic divisions of the autonomic nervous system and their influence on the heart rhythm for prevention of complications with hypodynamia. The effectiveness of IPC was analyzed depending on the level of blood filling of the lower extremities, which will subsequently allow to determine the adaptive capabilities of the body and show a differential assessment to prevent further vascular dysfunction. It was established that a special contribution to increasing the therapeutic effect on central hemodynamics, especially on blood pressure, belongs to the parameters of the pressure in the cuffs of the IPC device and the duration of the procedure. Thus, in order to achieve a lower impact on central hemodynamics, the compression in the cuffs should be reduced to values less than 40 mm Hg and accordinly increase the time of the procedure to correct the functional state of the body. There was a study of changes in blood pressure when using the method of IPC on the venous system of the lower extremities in people with chronic venous insufficiency, depending on the pressure parameters that lead to hypo- and hypertensive effects, with further recommendations for the prevention of venous insufficiency of the lower extremities.