Dissertation work is devoted decline of frequency of premature labours
for women with a retrochorial haematoma in I trimester of pregnancy on the
basis of study of clinical and echographic, doppler, endocrinology, immunological and microbiological researches of researches, and also improvement
of algorithm of prognostic and treatment-and-prophylactic measures. For the
decision of the put purpose the followings tasks were certain: to conduct to the
estimation of structure of retrochorial haematomas in I trimester of pregnancy;
to set the leading echographic criteria of retrochorial haematomas in I trimester;
to find out features system to hemostasis for pregnant with the threat of
terminating pregnancy and retrochorial haematoma in 1 trimester; to rotin the
role of dyshormonal and disimmunological violations in genesis of retrochorial
haematoma in І trimester of pregnancy; to perfect the mathematical model of
prognostication of development of retrochorial haematoma in I trimester for
pregnant with the threat of terminating pregnancy; to estimate efficiency of the
improved algorithm of treatment-and-prophylactic measures for women with a
retrochorial haematoma in I trimester.
A research object is premature labours. The article of research is motion
of pregnancy and labours at retrochorial haematoma in I trimester of pregnancy.
Research methods – clinical, echographic, cardiotocographic, doppler, endocrinology, immunological, microbiological, morphological and statistical.
For achievement of the put purpose research was up-diffused on the
stages on each of which certain objects and research methods. A research
design foresaw three stages. On a 1 stage the methodical going near the
leadthrough of research, certain purpose and task, tool, conducted analysis of
literary sources were developed. On 2 stages collection of research materials
and executed analysis of the got data, expected indexes, which characterize
processes which are studied, is executed. The result of 3 stages of research was
development of recommendations in relation to the increase of efficiency of
the differentiated approach to therapy of threatening abortion for pregnant with
retrochorial haematomas. Research program clinical-anamnestic features
of motion of threat of terminating pregnancy depending on the fact of forming
retrochorial haematoma, echographic parameters of development of embryo
and extraembrionic structures, hemostasiological, hormonal and infectious
status of pregnant. As a result of the executed research of the marked objects
with the use of the adopted methods there were the grounded recommendations
in relation to the differentiated going near treatment of threatening abortion for
pregnant with a retrochorial haematoma. All expectant mothers (120 women)
were up-diffused on four groups. In a group 1 comparisons included expectant
mothers which were on stationary treatment concerning the threat of terminating pregnancy with the presence of retrochorial haematoma and got the
algorithm improved by us. The quantity of group made 30 expectant mothers.
As plugging criteria in this group were the followings signs: term of pregnancy
6-12 weeks (I trimester), presence of clinical and ultrasonic signs of threat of
terminating pregnancy, presence of retrochorial haematoma, the fact of presence
of which was confirmed during ultrasonic research, complete implementation
of the algorithm of chart of complex therapy improved by us. In group 2
comparisons included expectant mothers which were on stationary treatment
concerning the threat of terminating pregnancy with the presence of
retrochorial haematoma, that got the generally accepted treatment. A quantity
made 2 groups 30 expectant mothers. As plugging criteria in this group were
the followings signs: term of pregnancy 6-12 weeks (I trimester), presence of
clinical and ultrasonic signs of threat of terminating pregnancy, presence of
retrochorial haematoma, the fact of presence of which was confirmed during
ultrasonic research, implementation of chart of the generally accepted therapy.
In group 3 comparisons included expectant mothers which had a threat of
terminating pregnancy in anamnesis. The quantity of group made 30 expectant
mothers. As plugging criteria in this group were the followings signs: presence
of clinical and ultrasonic signs of threat of terminating pregnancy in the term
of pregnancy 6-12 weeks (I trimester), absence of retrochorial haematoma,
implementation of the generally accepted chart of treatment of threat of
terminating pregnancy. In group 4 included expectant mothers, motion of
pregnancy of which was not complicated by the threat of terminating
pregnancy. The quantity of group made 30 expectant mothers.
