Roshchupkin A. Neurohumoral regulation of intrarenal hormone systems and cystic transformation of kidneys

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0400U000964

Applicant for

Specialization

  • 14.03.04 - Патологічна фізіологія

27-03-2000

Specialized Academic Board

Д 41.600.01

Odessa National Medical University

Essay

The ontogenetic peculiarities of biosynthesis of prostanoids in the cortex and medulla of the kidney were revealed and their interrelation with main exponents of kidney s fuction. The regulative influence of endogene opioids both on the system of renal prostanoids and on the level of " secondary masangers" has determined. a wide comparative evaluation of the activity of some hormone systems in patients with different renal pathology was carried out. Data about the level of prostanoids in cysts contents taken in punction capture l were received. Increased activity of hypothalamus-hypophysar system in polycystic kidney disease. Key words: prostaglandins, kidney, opioids, polycystic kidney disease.

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