Prybylova O. Hormonal disorders and their correction with the use of heterotopic transplantation of cryopreserved placental tissue in women with pathological climacteric

The thesis contains the results of complex clinical, laboratory, instrumental and hormonal study of 130 climacteric women. 100 patients had pathological climacteric and 30 women physiological course of climacteric. The main aim of this study was the analysis of influence of heterotopic transplantation of cryopreserved placental tissue (HTCPT) on b-endorphin and hormone levels in the blood serum and clinical course of climacteric syndrome in woman with climacteric syndrome (CS) in woman with pathological climacteric. The effective scheme of correction of climacteric disorders has been worked out. It was established that the levels of cortizol and b-endorfine changed under the influence of cryopreserved placental tissue. These changes illustrate normalization of broken mechanisms of adaptation. The best therapeutic effect was observed in clinical group 3. The patients in this group were climacteric and suffered from CS, for their treatment HTCPT was used