Mel'nikova O. The role of dorsal motor vagus nucleus and locus coeruleus on endocrine pancreas regulation in the norm and experimental diabetes mellitus

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0400U003363

Thesis Registration Form

0400U003363.pdf

Applicant for

Specialization

  • 14.03.04 - Патологічна фізіологія

28-11-2000

Specialized Academic Board

Д 26.198.01

Bogomoletz Institute of Physiology National of science of Ukraine

Essay

It is shown that reaction of dorsal motor nucleus of the vagus nerve (DMN) and locus coeruleus is dependent on the degree of diabetes severity and its type (insulindependent or noninsulindependent). Hypoxic trainings in normal and diabetic animals results in activation of DMN that leads to increasing of insu-lin synthesis and secretion. In experiments with vagotomy in intact and diabetic rats the direct influence of the vagus nerve on the functional state of Langerhans b- and a-cells is shown/

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