Kulagina I. The impact of geometry of the dendrites with tonically activated conductances on the formation of electrical activity of neurons: a simulation study

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0401U000417

Thesis Registration Form

0401U000417.pdf

Applicant for

Specialization

  • 03.00.02 - Біофізика

26-12-2000

Specialized Academic Board

Д 26.198.01

Bogomoletz Institute of Physiology National of science of Ukraine

Essay

Elementary increment of the core current was proved a universal estimate of the current transfer effectiveness in the dendrites of arbitrary geometry and membrane properties. The link is found between the geometry, the type of the local steady current-voltage relation of the membrane, and the somatopetal current transfer effectiveness of different sites of a dendritic arborization during tonic distributed excitation. It was demonstrated that the structural asymmetry of neurons, particularly the branching asymmetry, defines the effectiveness of different parts of a dendritic field.

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