Gladkykh I. Plasmapheresis in complex intensive therapy of a burn shock at children.

The thesis is devoted to problems of еаrly application efferent method of detoxification - membrane plasmapheresis - at heavy and heaviest burn shock at children. Results of this work are conducted clinical, biochemical, immunological researches current of the burn illness treated with the routine methods and by application membrane plasmapheresis. In this work the basic positions about pathophisiology mechanisms of development intoxication are formulated, terms and criterions of development endotoxemia are detected. The modulating influence of membrane plasmapheresis on an immune system, function of a liver and kidneys, on a character of inflammatorily and regeneration in a wound were revealed. As a result of early application membrane plasmapheresis in complex intensive therapy burn shock at children the amount of complications is reduced, the outcomes of treatment and survival are improved.