Nasrin K. A clinical and experimental basis of low uretine activity in labor liposomal therapy

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0401U000880

Applicant for

Specialization

  • 14.01.01 - Акушерство та гінекологія

08-02-2001

Specialized Academic Board

Д 64.600.01

Kharkiv National Medical University

Essay

Object of the investigation - morphofunctional characteristic of fetoplacental system state and myometrium providing uterine activity in labor. With the purpose of refinement reduced of uterine activity in labors on the basis of enriching hemodynamic, metabolic and immunological processes in myometrium and fetoplacental complex with the help of phosphatidylcholin liposomes and development of optimal method of labor activation the morphology of tissues of afterbirth and myometrium, immunomorphology, biochemical parameters (concentration of enzymes, ATP and ionized calcium in a blood plasma and homogenates of a myometrium), cardiotocography and partography parameters were investigated. Research of morphological characters of delicacy of uterine activity, aboriginal immune responses for muscles of uterus and tissues of placenta under influence of liposomal therapy for the first time were fulfilled, is proved doubtless immune effect of "Lipinum". It has allowed to develop diagnostic criteria of assessment of efficacy of offered method labor activation. And also most successful mode of intensifying of uterine activity in labors. The obtained data are introduced into work of maternity homes of Kharkov.

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