Ryeznikov V. Pharmako-biophysical characteristic of potential-gated ionic currents in smooth muscle cells of the rat tail artery.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0401U001664

Thesis Registration Form

0401U001664.pdf

Applicant for

Specialization

  • 03.00.02 - Біофізика

22-05-2001

Specialized Academic Board

Д 26.198.01

Bogomoletz Institute of Physiology National of science of Ukraine

Essay

Pharmacological and biophysical properties of the transmembrane ionic currents in smooth muscle isolated cells from the rat tail artery have been studied in the present work using patch-clamp recording techniques. There were revealed that integral transmembrane ionic currents consists of inward and outward components. The last consists from transient and stationary component. Transient component is caused by activation K(Са2 +) current. There was shown that phenylephrine blocks calcium-dependent potassium current.

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Files

Disser2.doc

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