Grebin' M. Haemodilution in anaesthesiological providing of microsurgical autotransplantation of the composite tissue complexes.

The thesis deals with the problem of anaesthesiologic providing of free microsurgical flap transfers. With the purpose to increase the efficiency of such operations clinical, functional and biochemical investigations were performed in four different infusion programs. On this basis the microcirculation particularities in free flaps at different stages of transplantation were studed. The volume, proper components and rate of the infusion during each infusion program were well-grounded and measured. The most effective infusion program was worked out and clinically tested with good results. The wide application of this program in clinical practice made it possible to decrease flap necrosis complications on 5,6% and achieve functional reabilitation in 88,8% of patients.