Gancheva O. The effects of chronic oxytocin and vasopressin administration on the state of pancreatic alfa and beta-cells and magnocellular hypothalamic neurons in the norm and experimental diabetes mellitus

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0402U000658

Thesis Registration Form

0402U000658.pdf

Applicant for

Specialization

  • 14.03.04 - Патологічна фізіологія

14-02-2002

Specialized Academic Board

Д 41.600.01

Odessa National Medical University

Essay

Oxytocin and vasopressin influence differently on pancreatic alfa- and beta-cells and magnocellular hypothalamic neurons. It was proved for the first lime that influence depends on the method of injection, state of animals, localization of the investigated neurons. It was shawn that in diabetes mellitus oxytocin oppositely to vasopresssin not only stimulate pancreatic insulin synthesis and secretion but also brakes pancreatic destruction and stimulate beta-cells proliferation with intracerebroventricular injection.

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Files

aref.doc

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