Lapshyn O. Prognosis of myocardial infarction and its complications by mathematical modelling

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0402U001045

Applicant for

Specialization

  • 14.01.11 - Кардіологія

21-03-2002

Specialized Academic Board

Д 26.003.04

Bogomolets National Medical University, Ministry of Health of Ukraine

Essay

The datas regarding determination of major risk factor of different acute myocardial infarction complications as well as uneventfull course are presented in this thesis. After calculating of correlation coefficients and relationships linear regression prognostic models were created. The testing of these prognostic models was performed in "retrospective" and independent cohorts of patients. The high prognostic accuracy of proposed models in terms of sensitivity, specificity, positive and negative predictive values for stratification of high, moderate and low risk of prognosed end-points was shown. We found statistically significant corellation among pretest probability of left ventricle failure-related end-points risk and intracardiac hemodynamic parameters. Prognostic significance of Selvester QRS score, non-invasive marker of myocardial necrosis, was further established.

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