Kubant R. Disturbances of free radical oxidation and energy processes in pathogenesis of toxic hepatitis in intoxication caused by hydrazine hydrochloride and cadmium chloride and their correction.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0402U001518

Applicant for

Specialization

  • 14.03.04 - Патологічна фізіологія

26-04-2002

Specialized Academic Board

К 58.601.01

Essay

The dissertation is dicated to the studying of free radical and energy oxydation in liver and blood plasma of different age rats in combine action of hydrazine hydrochloride and cadmium chloride and correction of disturbances by metall-complexes and unithiole. Combine effect of hydrazine and cadmium chloride was found to result in violations of tissue respiration processes and oxidative phosphorilation as well as activation of free radical oxidation both lipids and proteins. The using of unithiole, histidine and copper or zinc histidinate results in the normalization of pathological changes found in different age intoxicated animals.

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