Lisitsa A. The physics-chemical characteristic of biologically active substances based on the data of tіme-of-flіght plasma desorptіon mass spectrometry

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0402U003624

Applicant for

Specialization

  • 03.00.02 - Біофізика

25-11-2002

Specialized Academic Board

Д 26.001.38

Taras Shevchenko National University of Kyiv

Essay

Were research with method plasma desorptіon mass spectrometry (PDMS) for definition of a structure, condition, possible interactions of molecules of biologically active substances in a number of medical-preventive preparations, condition and dynamics of their changes in time in multicomponent modelling mixes, in CO2-extracts, in substation containing poison of mushrooms are analysed. The method PDMS is could be applied to optimal selection of components, stabilizers and prolongators of action by development and tests of new multicomponent of medical-preventive preparations, theoretical substantiation and forecasting of their structure. It was mount, a result PDMS depends, at а first time, of organic acids; of reactions in a gas phase, of factors of homo- and heteroclasters association of ions depends on degree of gidrofilum of substance; of substances with radioprotective or radiosensitive properties.

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